What are Hydroxychloroquine and Chloroquine? Could It Cure The Coronavirus?, Hydroxychloroquine For Coronavirus, Hydroxychloroquine Side Effects
What Is Hydroxychloroquine Used For?
Hydroxychloroquine is a medicine used to treat and heal malaria in areas where malaria persists sensitive to chloroquine. It is taken by mouth. Additional uses include medicine for lupus, rheumatoid arthritis, and porphyria cutanea trade.
Why There Is A Hype Of Hydroxychloroquine?
The United States is fast-tracking antimalarial drugs for use as a medicine against the new coronavirus (COVID-19), American President Donald Trump said, following encouraging and supporting early results in China and France.
Hydroxychloroquine and Chloroquine have not been given a confirmed green light in the United States to fight the epidemic, but the FDA (Food and Drug Administration) said it would work with domestic makers to grow production as it studied their effectiveness.
The news came as Senate Republicans revealed a 1 trillion dollar emergency relief package to fight the economic turbulence caused by the COVID-19 which must now be investigated by so-far dubious Democrats, who want to include direct economic aid to individuals before a date can be set for a vote.
Both drugs mentioned by US President are already approved for lupus, malaria, and rheumatoid arthritis, and doctors in the United States may prescribe any drug they consider is appropriate medically.
"We will be ready to make that drug available almost instantly, and that is where the Food and Drug Administration has been so great," Trump said, pointing to both compounds. (Hydroxychloroquine and Chloroquine).
The United States has recorded over 367,758 cases of new coronavirus infection, 10,981 of them fatally, as of April 7, 2020. But officials expect the number to increase steeply in the coming days because of increased levels of testing after primary delays.
Food and Drug Administration Commissioner Stephen Hahn said; "If there is an experimental drug that is possibly available, a doctor could ask for that drug to be used in a victim. We have guidelines for that and quick approval.
Food and Drug Administration Commissioner Stephen Hahn said; "If there is an experimental drug that is possibly available, a doctor could ask for that drug to be used in a victim. We have guidelines for that and quick approval.
For example, many Americans have read studies and heard media reports about this drug Hydroxychloroquine and chloroquine, which is an anti-malarial drug.
This is a drug that president Trump directed us to inspect, whether an expanded use approach to that could be done to see if benefits victims.
Hydroxychloroquine and chloroquine are synthetic forms of quinine, which is detected in the barks of cinchona trees of Latin America and has been used to treat malaria disease for centuries.
Some in the broader scientific community have cautioned more research and analysis is needed to prove that they work and are safe for Coronavirus (COVID-19).
Sanofi (French drugmaker) said; it was available to offer the French government millions of doses of hydroxychloroquine, sold under its brand name Plaquenil, considering 'promising' research carried out by scientists Didier Raoult of the IHU Hospital in Marseille, France.
Didier Raoult announced this week that after treating twenty-four patients for 6 days with Plaquenil, the virus had gone in all but a quarter of them.
The research and analysis have not yet been published or peer-reviewed, and Raoult had come under storm by some officials and scientists in his native France for potentially proposing false hopes.
Didier Raoult said in Agence France-Presse; "I am just doing my duty, and I am glad to see that now 8 or 9 countries recommend hydroxychloroquine or chloroquine treatment for patients with this new coronavirus (COVID-19).
Supportive/Encouraging - Hydroxychloroquine and Chloroquine
Some clinical experiments are also underway in China, where officials have announced positive results but not yet announced their data.
The University of California, Riverside's professor Karine Le Roch, told Agence France-Presse she was encouraged by recent work in China and France.
She said; "I will say there are fewer patients, but if the outcomes (results) are accurate, it seems to definitely reduce the viral loads of infected patients.
"It is supportive but we have to make sure the effects are correct and then confirm that with a larger number of sufferers."
Experts understand how these alkaloids (naturally occurring organic compounds that mostly contain basic nitrogen atoms) work at the cellular level to combat malaria parasites, but it is not yet known how they are combating the coronavirus, Le Roch added.
"This alkaloid may change the acidity of the cells affected with the virus," she told Agence France-Presse.
"And then the enzymes (proteins and biological catalysts) that are required for the virus to replicate cannot work as accurately as they would work without the drug."
But Not Everyone Convinced - Hydroxychloroquine and Chloroquine
Xavier de Lamballerie and Franck Touret - French Scientist; urged caution, noting that hydroxychloroquine and chloroquine had been proposed several times to treat serious viral diseases in humans without success, including HIV positive.
They said finding the correct dose was crucial because "Hydroxychloroquine or chloroquine poisoning has been linked with cardiovascular diseases that can be life-dangerous."
Aftereffect/Side Effects Hydroxychloroquine and Chloroquine
Many countries have now started on clinical tests, including America, where one began in New York this week. Italy is carrying out a test on two thousand people, while experts are also awaiting the results from bigger tests in China. But while the drugs are being rolled out for tender use, it is important to remember safety precautions.
Related Articles:
About 1% of people are at high risk of seizure, blackouts, or even unexpected death from cardiac arrest because of heart rhythm issues they may themselves be ignorant of, Michael Ackerman, a genetic cardiologist at Mayo Clinic said Agence France-Presse.
Ackerman said; Medicinal teams must, therefore, perform electrocardiograms to notify their danger analysis ere using these medicines (Hydroxychloroquine and Chloroquine), he said. "All focal point is placed on the hope for healing efficacy of these medicines, with no reasonable amount of respect, not fear, but respect for what the possible side effects of these powerful medications are."
Tags: Hydroxychloroquine, Chloroquine, Hydroxychloroquine Uses, Hydroxychloroquine Effects, Hydroxychloroquine Side Effects, Hydroxychloroquine For Coronavirus, Hydroxychloroquine For COVID-19
